Recent research lead by Associate Professor Simon Knowles at Swinburne University has made significant strides in understanding and measuring “brain fog” among individuals with coeliac disease. This cognitive symptom, often described by patients as a confusing and frustrating side effect of gluten exposure, has long been difficult to quantify in clinical settings.
Knowles and his team, in collaboration with Coeliac Australia and its members, have developed a validated scale to assess the severity of brain fog. This initiative began with insights from a presentation at a past Coeliac Australia expo, which highlighted the need for a systematic way to measure this elusive symptom. The research involved gathering firsthand accounts from individuals experiencing brain fog, which were then used to craft a comprehensive survey to assess its psychometric properties.
The project exemplifies the value of collaboration in medical research. Knowles worked closely with Jason Tye-Din from WEHI and other colleagues from Swinburne, their efforts supported by funding from Coeliac Australia. The tool is a testament to the power of community involvement in research, with involvement from Coeliac Australia members cited as pivotal to this project.
The result is a freely available tool that can reliably measure brain fog across different contexts—not just in coeliac disease but potentially in other conditions as well. The scale not only offers a method to track and assess the symptom but also brings much-needed attention to a frequently overlooked aspect of patient well-being.
Meet the researcher – Simon Knowles
Associate Professor Simon Knowles has dedicated over two decades to exploring the intricate relationship between the brain and the gastrointestinal tract. His interest in gastroenterology was sparked during his PhD, which investigated the psycho-biological impacts of shift work, including its effects on gastrointestinal health.
Knowles’s career has been characterised by a deep fascination with how psychological processes influence gastrointestinal symptoms and vice versa. His work focuses on helping individuals cope with, and adapt to, the challenges of living with gastrointestinal conditions such as coeliac disease.
By developing strategies and tools to mitigate these challenges, Knowles aims to improve his patients’ quality of life.
His recent work on brain fog highlights his commitment to addressing both the physical and psychological impacts of gastrointestinal conditions. This work, supported by collaborations with Coeliac Australia and its members, reflects his passion for making meaningful, practical contributions to the field and to the lives of those affected by these conditions.
